3-Thiophenecarboxylic acid, 2-methyl-, methyl ester

3-Thiophenecarboxylic acid, 2-methyl-, methyl ester - Names and Identifiers

Name	2-Methyl-3-thiophenecarboxylic acid methyl ester
Synonyms	Methyl 2-Methyl-3-thiophenecarboxylate Methyl 2-methylthiophene-3-carboxylate 2-Methyl-3-thiophenecarboxylic acid methyl ester 3-Thiophenecarboxylic acid, 2-methyl-, methyl ester 2-Methyl-3-thiophenecarboxylic acid methyl ester 3-thiophenecarboxylic acid, 2-methyl-, methyl ester
CAS	53562-51-9
InChI	InChI=1/C7H8O2S/c1-5-6(3-4-10-5)7(8)9-2/h3-4H,1-2H3

3-Thiophenecarboxylic acid, 2-methyl-, methyl ester - Physico-chemical Properties

Molecular Formula	C7H8O2S
Molar Mass	156.2
Density	1.173±0.06 g/cm3(Predicted)
Boling Point	90-91 °C(Press: 17 Torr)
Flash Point	76.216°C
Vapor Presure	0.293mmHg at 25°C
Storage Condition	2-8°C(protect from light)
Refractive Index	1.532

3-Thiophenecarboxylic acid, 2-methyl-, methyl ester - Risk and Safety

UN IDs	1993
Hazard Class	3
Packing Group	Ⅲ

3-Thiophenecarboxylic acid, 2-methyl-, methyl ester - Introduction

Acid methyl ester is an organic compound whose chemical formula is C9H9O2S. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: acid methyl ester is a colorless liquid or pale yellow oily substance.
-Solubility: acid methyl ester is soluble in organic solvents such as ethanol, acetone and ether, but insoluble in water.
-Molecular structure: Its molecular structure includes a methyl ester group and a thiophene ring.

Use:
-acid methyl ester is widely used in the field of organic synthesis and can be used as an intermediate for the synthesis of other organic compounds. It can participate in esterification reaction, sulfonation reaction, Grignard reaction and other organic synthesis reaction.
-The compound can also be used in chemical fields such as drug synthesis and dye synthesis.

Preparation Method:
-the preparation method of acid ester is usually obtained by SN2 substitution reaction between thiophene and bromoacetate.
1. First, under an inert atmosphere, thiophene and bromoacetate are reacted in the presence of an acid catalyst or a base catalyst.
2. After the reaction is completed, the intermediate product is hydrolyzed to obtain acid methyl ester.

Safety Information:
-the acid ester should be stored in a cool, dry place, away from fire and oxidizing agents.
-When operating, wear protective glasses and gloves, and ensure a well-ventilated laboratory environment.
-acid methyl ester may be irritating to the skin, eyes and respiratory tract and should be avoided.
-When handling the compound, follow appropriate safe operating procedures and comply with relevant regulations and specifications.

Last Update：2024-04-09 21:01:54